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Steam Thru Series Connector

Steam-Thru Connections allow a quick and easy sterile connection between stainless steel biopharmaceutical processing equipment and disposable bag and tube assemblies. The single-use design saves time and money by eliminating unnecessary cleaning procedures and reducing validation burden associated with reusable components.

FEATURES BENEFITS
Innovative three- port design

Allows a true steam-through SIP process which eliminates "dead legs" and the need for laminar flow hoods

Patented valve design Allows sterile connection and disconnection and permits high media flow rate
Thumb latch/Tear-away sleeve      Secures valve position, provides visual indicator of process stage
3/4" and 1-1/2" Terminations  Easily connects to process equipment
ADCF-free materials Meet BSE/TSE requirements

 

 

Pressure

Steam position:
Up to 30 psi, 2.1 bar (Steam-Thru)
Up to 35 psi, 2.4 bar (Steam-Thru II)
Flow position: Vacuum to 20 psi, 1.4 bar

Temperature

Steam position:
Up to 266°F (130°C) for 60 minutes (Steam-Thru)
Up to 275°F (135°C) for 60 minutes (Steam-Thru II)
Flow position: 39°F to 104°F (4°C to 40°C)

Sterilization

Gamma: Up to 50 kGy irradiation
Autoclave: Up to 265°F (129°C) for 60 minutes, up to two cycles (applies only to
part numbers STC1700500-STC1700800 and STC2020000-STC2021000)
SIP process:
Up to 266°F (130°C) for 60 minutes (Steam-Thru)
Up to 275°F (135°C) for 60 minutes (Steam-Thru II)

Termination Sizes

3/8" (9.5mm) to 1/2" (12.7mm) ID hose barb (Steam-Thru)
3/8" (9.5mm) to 1/2" (12.7mm) ID hose barb and 3/4" sanitary (Steam-Thru II)

MATERIALS:

 

Connection:       

Polysulfone (amber tint), USP Class VI, ADCF

O-rings:

Silicone (clear), platinum-cured, USP Class VI, ADCF

Tear-away sleeve:

Polyethylene or polycarbonate (Steam-Thru only), USP Class VI

Typical Flow Rate       

CV = 4.2 - 4.6 (Steam-Thru)
CV = 5.2 - 8.0 (Steam-Thru II)

 

 

Steam-Thru® IConfigurations
Steam-Thru Connection’s patented three-port design allows steam to pass directly through the lower ports to "steam on" to stainless equipment.
After the SIP cycle is completed, the connector’s valve is actuated, creating a sterile flow path to single-use systems. 

Steam-Thru II Configurations
Steam-Thru II Connections offer the flexibility of "steam on" and "steam off" functionality. The innovative design allows the valve to be returned to the steam position enabling a second SIP cycle following media transfer. The "steam off" disconnection of single-use systems minimizes cross-contamination risks associated with reusable components.

 

Seed Trains 

 

Fermentation seed train with stainless bioreactors

 

Final Fill Finish 

 

Final Fill with Mobile Bulk Storage Vessel