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Sterile Disconnector – HFC39 Series

HFC39 Series sterile disconnect couplings prevent external organisms from entering into the media flow path upon disconnection. Automatic shutoff valves close off the flow path aseptically protecting valuable media while also eliminating the need for pinch clamps and tube welders. The easy-to-use thumb latch design provides a secure, leak-free connection and enables one-hand disconnects.



Simple one-step disconnection

Maintains media sterility in each half by preventing external organisms from entering the flow path

Automatic shutoff valves

Stop flow and eliminate need for pinch clamps

CPC Click    

Audible confirmation of secure connection


Easy integration with single-use assemblies

ADCF-free materials

Meet BSE/TSE requirements


Vacuum to 125 psi, 8.6 bar


-40°F to 280°F (-40°C to 138°C)


Gamma: Up to 50 kGy irradiation. Sterilize coupled or uncoupled.
Autoclave: Up to 270°F (132°C) for 60 minutes. Up to 25 repetitions for uncoupled units and up to one repetition for coupled units.

Termination Sizes            

1/4", 3/8" and 1/2" ID hose barb (6.4mm, 9.5mm and 12.7mm)



Main Components:

Polysulfone (amber tint), USP Class VI, ADCF


Silicone (clear), platinum-cured, USP Class VI, ADCF


316L stainless steel



Filter Integrity Testing 


Aseptic Disconnection Filter Integrity Testing



Final Fill Finish Operations


Final Fill with Mobile Bulk Storage Vessel